Summary:
Circulate Health raises $12M in seed funding for its plasma exchange services aimed at longevity.
Therapeutic plasma exchange could reduce biological age by 2.61 years, according to a recent study.
Treatments cost $8,000-$10,000 per session and are not covered by insurance.
Experts caution that longevity benefits are not yet proven, citing study limitations.
Part of the booming longevity tech sector, which saw $1.8B in investments recently.
Circulate Health, a Seattle-based startup focused on health longevity, has recently secured $12 million in seed funding to expand its innovative plasma exchange services. This groundbreaking approach aims to offer a 'blood-cleaning' service designed to promote longer, healthier lives.
The Science Behind the Service
Circulate Health utilizes machines for therapeutic plasma exchange, a process that removes a patient’s blood, separates the plasma, and returns clean blood cells with a replacement protein fluid. This method targets the removal of inflammatory factors and aging-related biological compounds.
- Recent Study: A study involving 42 adults showed potential benefits, with participants receiving plasma exchanges and antibodies showing an average biological age reduction of 2.61 years.
- Cost: Treatments range between $8,000-$10,000 per session and are currently not covered by insurance.
Challenges and Criticisms
Despite promising results, the study's small size and short duration raise questions. Experts, including Dr. Jeffrey Winters from the Mayo Clinic, caution that the longevity benefits are not yet proven.
The Bigger Picture
Circulate Health is part of a growing longevity tech sector, which attracted $1.8 billion in investments from 2021 to early 2025. The startup faces competition from clinics like MaxWell Clinic and Next Health.
Leadership and Vision
Co-founded by Dr. Brad Younggren and Dr. Eric Verdin, Circulate aims to pioneer outpatient plasma exchange services. Younggren envisions a future where such treatments could prevent costly diseases, offering both personal and economic benefits.
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